The invention provides an antistatic, anti-ultraviolet, antibacterial, breathable, skin-touch waterborne polyurethane coating adhesive and a preparation method thereof. The coating adhesive is prepared from, by weight, 20-30 parts of deionized water, 0.5-3.0 parts of diisopropyl octadecanalkoxyl acetyl aluminum chelate, 5.0-15 parts of modified hemp lignocellulose powder, 3.0-5.0 parts of polyurethane elastic powder, 50-70 parts of polyurethane adhesive, 0.1-0.3 part of defoaming agent, 1.0-5.0 parts of associative polyurethane thickener, 2.0-5.0 parts of anti-static agent, 5.0-10 parts of organic silicon smooth handfeel agent, 2.0-5.0 parts of organic silicon anti-sticking agent and 1.0-3.0 parts of ultraviolet absorbent in a compounding mode. The coating adhesive is suitable for pure cotton, polyester, chinlon and various blended fabrics and good in wear resistance and washability.