The invention provides a microphone signal control device based on a reactor control rod driving mechanism. The microphone signal control device comprises a remote control terminal and a local control terminal, wherein the local control terminal is connected with a microphone signal on the reactor control rod driving mechanism; the microphone signal on the reactor control rod driving mechanism is equidistantly divided into four zones on the basis of quadrant; each zone is respectively corresponding to one connector; the microphone signal is divided into nine groups as per SA, SB, SC, SD, R, N2, N1, G2 and G1 by each connector according to the attributive quadrant; rotary switches corresponding to the nine groups are respectively arranged on the remote control terminal and the local control terminal; the rotary switches are used for selecting the corresponding groups. The control on the microphone is realized, each connector is corresponding to one quarter reactor core, each set of signals are symmetrically weighted from one quarter reactor core, each set of signals comply with the reactor core power unfolding principle, and uneven reactor core power caused by independent test for one or more microphone in each group can be avoided.