The invention relates to a method for one-off collection of a plurality of data items. A terminal serving as a master station and a plurality of electric energy meters that serve as slave stations and are connected with the terminal by power lines are provided. The terminal initiates a electric energy meter data reading request, generates master station request messages, and sends the messages to the electric energy meters; the electric energy meters check master station request frames; when detecting identifiers for multi-data-item combined reading in data domains of the master station request frames, the electric energy meters carry out multi-data-item combined reading processing; the electric energy meters generate slave station response messages and upload the messages to the terminal; the terminal checks the returned slave station response messages; and when the identifiers for multi-data-item combined reading in slave station response frame data domains are detected, multi-data-item combined parsing processing is carried out. According to the method provided by the invention, the different types of data items of the electric energy meters can be read in a one-off manner, so that the utilization rate of communication resources of the system is improved, the system communication resources are dug fully, and the data acquisition efficiency is improved.