The invention discloses a two-way isolation switch and a GIS switchgear of using the same. The two-way isolation switch comprises a barrel, wherein the barrel comprises a shell and a telescopic joint; the shell and the telescopic joint are coaxially arranged at the rear side of the shell; a conductive rod assembly is arranged in the barrel and comprises a front moving contact block and a front moving contact; the front moving contact is arranged at the front end of the moving contact block in a guide motion manner; the conductive rod assembly comprises a rear moving contact block located at the rear side of the front moving contact block and a rear moving contact; the rear moving contact is arranged at the rear end of the rear moving contact block in a guide motion manner; the front side of the shell is connected with a first basin-type insulator; the rear side of the telescopic joint is connected with a second basin-type insulator; the first basin-type insulator is provided with a front fixed contact; and the second basin-type insulator is provided with a rear fixed contact. The two-way isolation switch is used for the GIS, so that the target of two-way isolation can be achieved, the two-way isolation switch can play a role in being dismantled from the position to maintain the GIS, a transition barrel in the prior art is replaced with the isolation switch and the two-way isolation switch is convenient to dismantle.