The invention provides a rubber plug oil removing machine and an application of the rubber plug oil removing machine to wire harness production. The rubber plug oil removing machine comprises a rolling device and a power device used for driving the rolling device to roll. A containing cavity is formed in the rolling device. An oil absorption object is arranged in the containing cavity. The power device is used for driving the rolling device to rotate, and the oil absorption object in the containing cavity makes full contact with a product with oil absorption required so as to achieve the oil removing purpose. The roller principle and side edge contact rolling principle are applied to the wire harness production, and thus an efficient production method is provided for the wire harness production technology process. By the adoption of the simple structure, automatic production of the rubber plug oil removing process is realized; and the whole device can only be driven by a motor, so that cost is low, power conversion efficiency is high, applicability is high, the production benefits are greatly increased, and industry development is facilitated.