The invention particularly relates to a special organic fertilizer for Moringa oleifera and a preparation method thereof. The organic fertilizer is prepared from the following components in percentage by mass: 20-30% of rape seed oil cake, 50-60% of tobacco waste and 10-20% of manioc waste. According the growth features of Moringa oleifera, the N, P and K are reasonably proportioned and evenly applied, thereby specifically providing the special organic fertilizer for Moringa oleifera. The special organic fertilizer for Moringa oleifera has the advantages of balanced nutrients and obvious yield increase effect, and can improve the quality of Moringa oleifera.