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发明授权
CN106520801B 苏氨酸衰减子的突变体及其应用以及解除苏氨酸操纵子反馈阻遏的方法 有权

苏氨酸衰减子的突变体及其应用以及解除苏氨酸操纵子反馈阻遏的方法
摘要：
本发明公开了一种解除阻遏的苏氨酸操纵子基因，自上游至下游依次包括元件甲和元件乙；所述元件甲如序列表的序列17第294至n1位核苷酸所示，n1为310以上336以下的自然数；所述元件乙为编码苏氨酸操纵子的基因。本发明还保护一种特异DNA分子，自上游至下游依次包括启动子和解除阻遏的苏氨酸操纵子基因。本发明还保护含有所述特异DNA分子的重组菌以及所述重组菌在生产苏氨酸中的应用。本发明在实践上可用于细菌发酵生产苏氨酸。
摘要（英）：

The invention discloses a threonine operon gene with repression removed. The threonine operon gene comprises an element A and an element B sequentially from upstream to downstream, wherein nucleotides of the element A are shown as 294th position to n1th position in the sequence 17 of the sequence table, wherein n1 is a natural number ranging from 310 to 336; the element B is a gene for coding a threonine operon. The invention further provides a specific DNA molecule which comprises a promoter and the threonine operon gene with repression removed sequentially from upstream to downstream. The invention further provides recombinant bacteria containing the DNA molecule and an application of the recombinant bacteria in threonine production. The invention can be applied to threonine production through bacterial fermentation.

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