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发明公开
CN106536552A 能够拮抗胰岛淀粉样多肽(IAPP)诱导的β细胞损伤和葡萄糖耐量受损的新的化合物 审中-实审

能够拮抗胰岛淀粉样多肽(IAPP)诱导的β细胞损伤和葡萄糖耐量受损的新的化合物
摘要：
所描述的是特异性地结合于人胰岛淀粉样多肽(hIAPP)，也称为胰淀素的分子，特别是用于拮抗作为通常与2型糖尿病(T2D)相关的症状的胰岛淀粉样多肽(IAPP)诱导的β细胞损伤和葡萄糖耐量受损的人源化抗体以及它们的片段、衍生物和变体。
摘要（英）：

Described are molecules specifically binding to human islet amyloid polypeptide (hIAPP) also known as amylin, particularly human-derived antibodies as well as fragments, derivatives and variants thereof for antagonizing islet amyloid polypeptide (IAPP) induced [beta]-cell damage and impaired glucose tolerance which are symptoms typically associated with diabetes mellitus type 2 (T2D).

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