The invention discloses a comprehensive stability estimation method of a DG-containing distribution network branch based on an equivalent nodal method, and belongs to the technical field of safety and stability estimation of a distribution network. The method comprises the following steps: acquiring voltage power flow information of a root node of the distribution network through calculation of power flow; establishing an equivalent model of a two-node power generation and transmission system on a node i; establishing an equivalent model of a two-node distribution network branch m; performing integration processing on the model and calculating equivalent parameters; calculating a comprehensive stability coefficient of the distribution network branch m according to the equivalent parameters; and acquiring a comprehensive stability coefficient value of the distribution network and the most vulnerable branch according to the comprehensive stability coefficients of all the branches. According to the comprehensive stability estimation method, the power generation and transmission system is introduced into a research object, and the accuracy of the estimation of the DG-containing distribution network is improved. Collaborative analysis of transmission and distribution ensures the economic and safe operation of a power grid; by definition of a brand-new voltage collapse coefficient and a load overload coefficient, the method realizes estimation of the voltage stability and the load carrying capacity of the power distribution network branch and enables the estimation to be more comprehensive.