The invention belongs to the technical field of bio-materials and relates to a bone repair adhesive capable of slowly releasing a growth factor and a preparation method thereof. In the invention, cyanoacetic acid is modified by heparin and then is further subjected to a reaction with formaldehyde to produce a heparinized cyanoacrylamide monomer that can support and slowly release the growth factor; the heparinized cyanoacrylamide monomer then is pre-polymerized under effect of methanol and supports the growth factor; the pre-polymerized product supported with the growth factors is finally mixed with the heparinized cyanoacrylamide monomer to produce the bone repair adhesive capable of slowly releasing the growth factor. The bone repair adhesive being capable of slowly releasing the growth factor can support and slowly release the growth factor, so that quick adhesion can be carried out and bone tissue repair is promoted during application of adhesion of bone and cartilage, bone tissue repair and the like; meanwhile, the bone repair adhesive has strong binding force, stable chemical performance and good bioavailability.