The invention discloses a multidimensional-adjustable laser beam sheet shaping device and method. The laser beam sheet shaping device comprises a beam sheet shaping lens group and a linear slide unit, wherein the beam sheet shaping lens group is composed of a shaping concave cylinder lens, a shaping convex cylinder lens, a beam expanding concave cylinder lens and a focusing cylinder lens in the light path direction in sequence. The linear slide unit adopts the ballscrew structure and is composed of a pedestal, screw rods and slide blocks, wherein the screw rods are fixed on the pedestal, the slide blocks are arranged on the screw rods, each slide block is provided with a lens installation hole, and the shaping concave cylinder lens, the shaping convex cylinder lens, the beam expanding concave cylinder lens and the focusing cylinder lens are installed in the lens installation holes. The device is simple in structure and easy to operate, the difficulty in operating the laser beam sheet shaping is effectively reduced, the quality and the stability of the sheet beam after beam shaping are improved, requirements for sheet beam output angles in different usage environments are met, and the device and the method are suitable for each filed of planar laser induced flourescense technology application.