利索-全球专利检索

  1. 登录
  2. 注册
发明公开
CN106573897A 作为mIDH1抑制剂的苯并咪唑‑2‑胺 有权 转让

作为mIDH1抑制剂的苯并咪唑‑2‑胺
摘要：
本发明涉及通式(I)的苯并咪唑‑2‑胺：其中 R1、R2、R3、R4、R5、R6、R7、R8、R9、R10、R11和R12如本文中所定义，涉及制备所述化合物的方法，涉及可用于制备所述化合物的中间体化合物，涉及包含所述化合物的药物组合物及组合并且涉及所述化合物作为单独试剂或与其它活性成分结合用于制造治疗或预防疾病（特别是赘生物）的药物组合物的用途。
摘要（英）：

The present invention relates to benzimidazol-2-amines of general formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.

公开/授权文献
0/0