The present invention discloses a radial micro-channel coupling reactor and applications thereof. The radial micro-channel coupling reactor comprises a cylindrical sealing pressure bearing shell, inlets and outlets for two kinds of raw material gases, and a radial catalysis reaction zone arranged in the shell, wherein the radial catalysis reaction zone comprises a plurality of radial micro-reaction channels coated with catalytic active components on the inner surface and the outer surface. According to the present invention, with the radial micro-channel coupling reactor, the two reactions such as heat release and heat absorption can be achieved in the one reactor, and particularly the reactor is suitable for one of the catalytic reactions having the significant volume change; the heat release reaction and the heat absorption reaction are integrally performed in the same reactor so as to simplify the original process and reduce the equipment cost; and the reactor has advantages of low catalyst active component consumption, high space utilization rate, high energy utilization rate, and high raw material conversion rate.