The invention provides a patterned glass bottle and a manufacturing method thereof, belonging to the technical field of glass bottle manufacturing. The patterned glass bottle is composed of inner-layer glass and outer-layer glass, wherein laminated glass is arranged between the inner-layer glass and the outer-layer glass, and the laminated glass has patterns. The manufacturing method comprises the following steps: (1) melting the raw material of the laminated glass, then putting a laminated glass blank into a mold, and blowing the laminated glass blank with the mouth to enable the laminated glass to be molded into a laminated glass bottle; (2) putting an inner-layer glass blank into the laminated glass bottle to obtain a glass bottle combining inner-layer glass and laminated glass; (3) hanging the glass bottle obtained in the step (2) in the mold, pouring the outer-layer molten glass into gaps, and cooling the molten glass for molding; and (4) sealing the glass bottle to obtain the required glass bottle. The glass bottle and the manufacturing method thereof have the advantages that the process is simple, the cost is low, built-in patterns are formed so as to increase the aesthetic feeling of the glass bottle and improve the grade of wine, and the anti-breaking effect is good.