The invention relates to the field of carbon dioxide flooding and discloses a carbon dioxide foam profile controlling method. The carbon dioxide foam profile controlling method comprises the following steps: carrying out carbon dioxide flooding in presence of a foam profile controlling agent, wherein the foam profile controlling agent contains a non-ionic oligomeric surfactant, an organic foam stabilizer and water, the non-ionic oligomeric surfactant has a structure in a formula (I) or a formula (II) shown in the specification, m is an arbitrary integer from 1 to 50, n is an arbitrary integer from 2 to 8, R1 is C4-C20 alkyl, R2 is polyether, a monomer forming the polyether is ethylene oxide and/or propylene oxide, and the polymerization degree of the polyether is 5-100. The foam profile controlling agent adopted in the method is low in usage amount in actual use, has good foaming capability and can be easily demulsified, the carbon dioxide foam profile controlling in the invention has good plugging and profile controlling capability, and according to the method disclosed by the invention, carbon dioxide foam flooding fluidity can be better controlled and carbon dioxide foam flooding recovery ratio can be increased.