The invention discloses a multi-power hybrid drive mechanism of a cooling tower. The multi-power hybrid drive mechanism comprises a spiral wind blade, a draught fan and a water turbine, wherein the axes of transmission shafts of the spiral wind blade, the draught fan and the water turbine are all positioned in the same vertical line; mechanical energy outputted by the spiral wind blade is superposed with that outputted by the water turbine; and the superposed mechanical energy is outputted to the draught fan, so as to drive the draught fan to work. The invention further discloses an automatic control method of the multi-power hybrid drive mechanism. The automatic control method comprises the following steps: (1) arranging a PLC (programmable logic controller), a temperature sensor and a rotating speed sensor; and (2) building a function about the contrast between variations in the water temperature T and the draught fan power P in the PLC, automatically calculating and adjusting the working state and the output/input power of a motor generator according to the function, and ensuring that the following dynamic balance among the power of the draught fan, the water turbine, the spiral wind blade and the motor generator can be automatically kept: delta T (water temperature) varies as delta P (draught fan), and delta P (draught fan) is equal to the sum of delta P (wind blade), P (water turbine) and delta P (motor generator) or the sum of delta P (wind blade) and P (water turbine) minus delta P (motor generator). Accordingly, water energy and wind energy can be utilized to the optimum extent.