The invention discloses a muckpile and scooping boundary measurement setting-out method; the method comprises: planning according to certain rules in accordance with the parameters, such as muckpile bulk coefficient, muckpile shape, scooping slope angle, and orebody occurrence state, measuring muckpile shape when rock-ore boundary is less than 10 m away from pre-blasting slope crest, and calculating a setting-out position by using the method of approach; when the rock-ore boundary is greater than 10 m away from the pre-blasting slope crest, calculating the setting-out position directly, wherein extrapolation distance is a distance from a boundary point to a part 2 m off the last row of hole lines, multiplied by bulk coefficient of this position. The problem of how to perform precise separate scooping and setting-out in rock-ore mixed blasting is well solved, mining loss is reduced, and dilution rate is reduced effectively; in addition, perforating efficiency of a related section is improved, perforating, blasting and scooping cycle time of the related section is shortened, and the productivity of an operation line is improved.