The invention discloses a production method, product, detection method and application of an electrochemiluminescence immunosensor based on CdTe@MOFs/CdTeQDs compound, and belongs to the field of electrochemiluminescence sensors. A metal-organic framework material is adopted to immobilize quantum dots, the special structure of the metal-organic framework material is used to immobilize the quantum dots in the metal-organic framework material and on the surface of the metal-organic framework material, the obtained composite material is used to immobilize a second antibody, a second antibody is immobilized under the assistance of a nano-gold functionalized titanium dioxide compound, and the obtained metal-organic framework material/quantum dot/antibody coupled compound and an antigen form a double-antibody sandwich immune reaction mode, so the identification and detection process of a target substance is realized, and the electrochemiluminescence signal is greatly enhanced. Effective detection of a biochemical marker is realized according to the intensity difference of the electrochemiluminescence signal of a substance-to-be detected with different concentrations.