The invention discloses a high-voltage fuse insulation handgrip and an application method thereof. The high-voltage fuse insulation handgrip comprises an insulation rod, an insulation protection layer, a through hole A, a through hole B, a cavity body, a handle, a base, a right clamp body, a left clamp body, a through hole C, an upper clamping piece D, an upper clamping piece E, a spring, a hauling cable, a pull handle, antiskid stripes and a baffle plate, and is characterized in that the outer wall of the insulation rod is provided with the insulation protection layer, the outer wall of the upper end of the insulation rod is provided with the through hole A, and the outer wall of the lower end of the insulation rod is provided with the through hole B; and the lower end of the insulation rod is provided with the handle, the upper end of the insulation rod is provided with the base, one end of the hauling cable successively passes through the inner side of the spring through the through hole B, the cavity body, the through hole A and the through hole C and is fixed at the inner side of the lower end of the left clamp body, and the other side of the hauling cable is provided with the pull handle. The advantages are as follows: personnel are kept at a corresponding safety distance during work, and personal safety is guaranteed.