The invention relates to a method for ensuring safe and reliable execution of a relay protection remote operation. A technical scheme based on determination on three aspects is disclosed; the determination on three aspects refers to conditions that at least three indications are changed correspondingly, and all the determined indications are all changed correspondingly at the same time; the safe and reliable execution of the remote operation function is protected, and then the purpose of improving the practical popularization of the relay protection remote operation is further fulfilled; and after the relay protection remote operation function is executed, the emergency handling capability of a power grid can be effectively improved, switching operation efficiency of the power grid is improved, manpower and material resource cost of a power supply enterprise is reduced, shutdown time of electrical equipment caused by accidents and other factors is shortened, traffic material loss is reduced, traveling risk of an operational and maintenance staff and personal risk of an onsite operator are lowered, and guarantee is provided for reliable power supply and good-quality service.