The embodiment of the invention provides a method and a device for processing registration and keeping alive. Network terminals or network exchange devices of a monitoring management system serve as registration authentication devices with a unified management platform, a network exchange device with initial registration success uses the management platform as a keeping-alive target device for keeping alive, the network terminal with the initial registration success is bound to a predetermined network exchange device in a registration message sending link, and keeping alive is carried out with the predetermined network exchange device bound with the network terminal as a keeping-alive target device. Occupancy of working resources in the management platform by registration and keeping alive can be effectively reduced.