The invention discloses an intelligent illumination control system of a power plant. An illumination operation station and an illumination logic controlling machine are connected with an Ethernet to form a background, and an illumination CPS in an illumination loop of the power plant is networked through a field bus, and then connected with the Ethernet after being communicated and integrated through an illumination communication gateway, and then interconnected with the background, wherein the logic controlling machine establishes a power plant illumination system model, and performs the formulation and the running of an illumination control strategy; the operation station performs automatic or manual control operation on the illumination loop according to the running strategy, and the data of the illumination loop acquired by the illumination communication gateway and the CPS switch. Therefore, the intelligent illumination control system is formed by reasonably modelling and adopting a concentrated control way, thereby realizing the intelligent control at different time, different regions and different loops on the whole power plant, the labor cost can be saved, the punctual and full-automatic control way is achieved, and the aims of prolonging the service life of the lamps and saving the power consumption for illumination are achieved at last.