The invention relates to a preparation method of skin-care cleansing oil wet wipe; the cleansing oil wet wipe is prepared by soaking nonwoven fabric in cleansing oil, and the cleansing oil is made from sumac fruit oil, olive oil, polyoxyethylene lauryl ether, dimeric surfactant, sumac leaf polyphenols, Chinese angelica extract, aloe oil, glycerol, sodium benzoate, and essential oil. The preparation method is simple, and the wet wipe has good stability and good affinity, has good cleansing effect and long shelf life, and rarely grows mildew; when applied to wiping or cleansing skin, especially skin and sensitive skin coated with high irritation cosmetic products, the cleansing oil wet wipe causes little irritation, rarely causes discomfort, and has good skin-care effect.