The invention discloses an internally-fixed and externally-fixed liquor box. The internally-fixed and externally-fixed liquor box comprises a box body. A bottom storage bin is arranged at the bottom of the box body. A liquor bottle storage bin is mounted on the bottom storage bin. An embedded cover body is arranged at the top of the box body. A big air bag is arranged on the bottom surface of the cover body. An inflation inlet of the big air bag protrudes out of the top surface of the cover body. An upper lock hook is arranged on the bottom surface of the cover body and located on the outer side of the big air bag. A pneumatic elastic lower lock hook which is clamped with the upper lock hook is arranged on the upper portion of the inner side of the box body. An inflation piece is arranged in the bottom storage bin. The pneumatic end of the pneumatic elastic lower lock hook is connected to the inflation piece through a pipeline. According to the internally-fixed and an externally-fixed liquor box, internal sealing and external sealing can be achieved, and the airtightness is good; and when a liquor bottle needs to be taken out, the inflation piece needs to be destructively taken out to inflate a small air bag so that it can be guaranteed that the box body can only be used once, and the safety is high.