The invention discloses a suspension bridge dehumidification control system based on a CAN bus. The system comprises integration data acquisition boxes, a dehumidification device, a CAN-to-Ethernet, and a host computer, wherein the integration data acquisition boxes, the dehumidification device and the CAN-to-Ethernet are connected through a CAN bus; and the host computer is connected with the CAN-to-Ethernet through Ethernet communication. Each integration data acquisition box comprises a main control chip, a CAN communication module, a power supply module, a sensor and a solenoid valve, wherein the CAN communication module, the power supply module, the sensor and the solenoid valve are connected with the main control chip; the sensor is installed on an air charging/discharging clip; and the solenoid valve controls an air charging/discharging switch. The integration data acquisition boxes sends acquired sensor data to the host computer and the dehumidification device through the CAN bus. Thus, traditional fiber communication, RS485 communication and power line carrier communication are replaced, so the whole suspension bridge dehumidification control system is more firm, and data interaction between nodes is quite easy, high in timeliness and quite convenient to control.