The invention discloses an anti-misoperation system for secondary plate pressing of an electric protection device. The anti-misoperation system is characterized in that an anti-misoperation system platform for secondary plate pressing of the electric protection device is constructed by establishing a basic database of the anti-misoperation system for secondary plate pressing of the electric protection device, formulating a logical checking process for anti-misoperation rehearsal of secondary plate pressing of the electric protection device and setting up an anti-misoperation rehearsal interface for secondary plate pressing of the electric protection device. In order to reduce the complexity of system implementation and simplify the software structure of the system, the anti-misoperation system adopts a modular design idea so as to divide the system into a data service module, an anti-misoperation process module and a user interface module from bottom to top. The anti-misoperation system disclosed by the invention has the advantages that the checking anti-misoperation rehearsal for the content of on-off operation of secondary plate pressing of the electric protection device in a switching-operation order can be realized, and simultaneously information services are provided for being convenient to intercept the on-off state of secondary plate pressing of the electric protection device and rechecking the correctness of the on-off state.