The invention discloses a winching machine-based self-protecting motor drive circuit system, which comprises an H-bridge drive circuit and a motor exception protection circuit, wherein P-channel enhancement MOS transistors and N-channel enhancement MOS transistors are utilized by the H-bridge drive circuit at the same time; the motor exception protection circuit comprises an RC filter circuit, a signal amplification circuit and a sampling circuit; and the H-bridge drive circuit is connected with the motor exception protection circuit in series. According to the circuit system, the problems of a motor failure, a power failure or jamming of a planet gear and the like are solved under the condition that the motor exceeds a rated load when running or the motor works in an overload condition for a long period of time. Furthermore, the circuit system integrates the P-channel enhancement MOS transistors and the N-channel enhancement MOS transistors, the problems of positive and negative rotation, braking and continuous speed regulation of equipment in a high-power DC motor in the using process can be effectively solved through the protection circuit, and the self-protecting motor drive circuit system has a self-protecting function.