The invention discloses an image sensor initial configuration method, an image sensor initial configuration device, an image sensor initial configuration circuit and a virtual reality device. The image sensor initial configuration method includes configuring a shutdown pin of an image sensor after powering on of a system power is completed; configuring the shutdown pin from low level to high level; configuring the image sensor after configuration of the shutdown pin is completed; displaying images normally after configuration of the image sensor is completed. The image sensor initial configuration method has the advantage that the shutdown pin of the image sensor is configured from the low level to the high level before the image sensor is configured and is in the high-level state constantly, so that the images of a camera can be displayed normally.