The invention relates to a pharmacological action of two traditional Chinese medicine monomer components and application of the two traditional Chinese medicine monomer components, in particular to a medicine taking arctiin and arctigenin as active components and application of the medicine in preparation of an anti-lung fibrosis drug. A research result shows that the arctiin can be partially metabolized into the arctigenin; the arctigenin is an active component enabling the arctiin to enter the blood; an in-vitro experiment shows that the anti-cancer effect of the arctigenin is obviously better than that of the arctiin. An in-vitro test result shows that the arctiin and the arctigenin thereof are relatively strong in effect of resisting lung fibrosis caused by bleomycin. The arctiin and the arctigenin are relatively high in activity in the aspect of resisting the lung fibrosis, have a small side effect, are low in cost and relatively high in druggability, and can be independently used for preparing or combined with other medicines for preparing the anti-lung fibrosis drug.