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发明公开
CN106692972A 含细胞自噬抑制剂的制剂及其在治疗气道粘液高分泌中的用途 有权 转让

含细胞自噬抑制剂的制剂及其在治疗气道粘液高分泌中的用途
摘要：
本发明提供了含细胞自噬抑制剂的制剂及其用途。具体地，本发明提供细胞自噬抑制剂在用于制备治疗气道粘液高分泌制剂中的用途，以及含有细胞自噬抑制剂作为有效成分的制剂。本发明的实验表明，细胞自噬抑制剂可以显著地降低动物模型中粘液蛋白MUC5AC的表达，进而显著缓解气道粘液高分泌。
摘要（英）：

The invention provides a cell autophagy inhibitor-containing preparation and application thereof, and particularly provides application of an cell autophagy inhibitor to preparation of a preparation for treating airway mucus hypersecretion as well as the preparation containing the cell autophagy inhibitor as an effective component. Experiments show that the cell autophagy inhibitor can significantly reduce expression of mucus protein MUC5AC in an animal model, and thus significantly alleviate the airway mucus hypersecretion.

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