The invention discloses an atomization preparation device for TiAl powder. The atomization preparation device comprises a furnace body, a smelting chamber, an atomization chamber and a collection chamber. The bottom of a smelting chamber crucible is connected to a liquid storage bag through a flow guide pipe. The bottom of the liquid storage bag is connected with a centrifugal nozzle through a flow guide pipe. The centrifugal nozzle is in a disc shape and is 10 cm in diameter. Four liquid discharge outlets are formed in the outer side of the centrifugal nozzle symmetrically and are 3 cm in diameter. The open direction of the liquid discharge outlets is the normal direction of the disc. A pulse-pressuring gas pipe is arranged above the centrifugal nozzle and is connected with a gas source. A control system controls the gas source to conduct pulse type pressuring on melt in the centrifugal nozzle. Four inert gas nozzles are arranged around the centrifugal nozzle correspondingly. The direction of the inert gas nozzles directly faces the throwing-out direction of melt at the liquid discharge outlets during rotation of the centrifugal nozzle. The collection chamber is arranged below the atomization chamber and is internally provided with a cyclone separator and an ultrasonic vibrating screen. Through the atomization preparation device, the crushing effect is improved, and the uniformity of powder is improved.