The invention provides an omni-directional LED lamp, the omni-directional LED lamp includes a tube, and there is a LED light source within the tube. The LED light source has at least one omni-directional LED light bar. Between the inner wall of the tube and the LED light source, it's filled with the light-permeable ceramic granular materials. The light-permeable ceramic granular materials are coated with the irregular surface which is contact with the LED light source. As a result, it can reduce the thermal resistance as well as increase the heat conduction. In order to get the reflection of diffused light, soften the light and prevent blue light from leaking out of the lamps, the light-permeable ceramic granular materials come up to our expectations.