The invention provides a reservoir high-precision prediction method under strong shielding. The method comprises the following steps that the seismic horizon of a strong reflection shielding layer above a reservoir on a seismic profile is picked up; static time shifting is performed on the seismic data by using the pickup seismic horizon; the seismic data after static time shifting is preprocessed by using median filtering so as to strip the strong reflection shielding layer; static reverse time shifting is performed on the seismic data after median filtering so as to obtain the seismic profile after removing of the strong reflection shielding layer; and the seismic attributes are extracted from the seismic data after removing of the strong reflection shielding layer, and the reservoir is carved so as to obtain a reservoir prediction result. Reservoir prediction under strong shielding is performed according to the method so that the reservoir identification capacity influenced by the effect of strong shielding can be greatly improved, the multiplicity of solution of seismic data reservoir interpretation can be reduced and the reservoir prediction accuracy under strong shielding can be enhanced.