The invention discloses an air pressure based power connection switch, and belongs to the technical field of switches. The air pressure based power connection switch comprises a piston rod, a conductive loop, a sealing ring, a casing, a casing cover and a spring, wherein the conductive loop is embedded in the casing, the piston rod and the sealing ring are mounted in the casing, the spring is connected between the piston rod and the bottom of the casing, and the piston rod, the sealing ring and the casing form a closed air chamber. According to the air pressure based power connection switch disclosed by the invention, change of air pressure inside and outside the air chamber when the switch enters upper air is utilized to drive the piston rod to move, so that the piston rod is in contact with the conductive loop to realize the function of the switch from off to on. The air pressure based power connection switch disclosed by the invention has a good reliability, and is applicable an application environment where the change of the air pressure is obvious.