The invention provides a load shedding scheme configuration method comprising the following steps: determining related parameters of an AC power receive channel, a DC power receive channel, a local power source and a transformer station in a receive end power grid; respectively calculating power transfer coefficients of the DC power receive channel, the transformer station, the local power source and the AC power receive channel; scanning fault types needing stable control measures; configuring effectively load shedding schemes according to the fault types needing stable control measures; determining the optimal load shedding scheme; verifying the operation mode rationality. The method and device can parse a power grid structure and operation modes, thus providing various quantification reference indexes for operation personnel, and greatly reducing simulation calculation work load in load shedding scheme configuration.