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发明公开
CN106727761A 七叶皂苷钠在制备治疗胃肠道平滑肌痉挛的解痉药物中的用途 无效 - 撤回

七叶皂苷钠在制备治疗胃肠道平滑肌痉挛的解痉药物中的用途
摘要：
本发明公开了七叶皂苷钠的制药新用途，尤其是在制备治疗胃肠道平滑肌痉挛的解痉药物中的新用途。七叶皂苷钠对乙酰胆碱致痉的胃底组织条有明显的降低张力作用，可用于胃肠道平滑肌痉挛所致急性肠胃炎、结肠炎、消化性溃疡、急性肠梗阻等疾病的治疗。临床试验表明：七叶皂苷钠对平滑肌痉挛所致胃肠绞痛有明显的治疗效果，总有效率达96.7％，与阿托品相比，疗效无显著差异但副作用更低。
摘要（英）：

The invention discloses novel pharmaceutical application of sodium aescinate and in particular discloses application of sodium aescinate in preparation of spasmolysis medicines for treating gastrointestinal smooth muscle spasm. The sodium aescinate has an obvious tension reduction effect on gastric tissue spasm caused by acetyl choline and can be used for treatment of diseases caused by gastrointestinal smooth muscle spasm such as acute gastroenteritis, colonitis, peptic ulcer, acute intestinal obstruction and the like. The clinical tests prove that the sodium aescinate has an obvious effect of treating gastric and intestinal colic caused by smooth muscle spasm, the total effective rate reaches 96.7%, and compared with atropine, the sodium aescinate does not have any obvious curative effect difference while is small in side effects.

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