The invention discloses a single-power multi-connection adjustable material transfer mechanism comprising a driving guide rail; the driving guide rail is sequentially provided with a first slide block, a second slide block, a third slide block and a fourth slide block and is slidably connected with the first slide block, the second slide block, the third slide block and the fourth slide block; the top of the first slide block is provided with a servo motor and a first clamping device, and the servo motor drives the first slide block to make reciprocating motion on the driving guide rail; the top of the second slide block is provided with a second clamping device; the side of the second slide block is provided with a first air cylinder locking mechanism; a first sliding rod is mounted on the first air cylinder locking mechanism and can slide on the first air cylinder locking mechanism or is locked on the first air cylinder locking mechanism; and the end, close to the first slide block, of the first sliding rod is fixedly arranged on the side of the first slide block. The single-power multi-connection adjustable material transfer mechanism is capable of guaranteeing the synchronism among the clamping devices and realizing adjustment by program control as well as high in position precision and automation degree.