The invention discloses a method for comprehensively recycling copper, nickel and iron from copper matte of a fuming furnace. The method is characterized by comprising the following technological steps: (1) crushing and ball grinding; (2) pressurizing and oxygen feeding for leaching; (3) copper electrowinnig; and (4) evaporative crystallization of nickel sulfate. According to the method, by the adoption of the pressurizing and oxygen feeding for leaching technology, the copper and the nickel in the copper matte of the fuming furnace can be effectively leached into a solution; cathode copper is produced through copper electrowinnig; after impurities such as arsenic and antimony are removed through electrowinning copper removal, the evaporative crystallization is carried out to produce a nickel sulfate product; and leaching residues can be used as a raw material for iron making of an iron and steel plant after being subjected to magnetic separation. The technology is short in process and high in valued metal recycling rate, can realize continuous and automatic production and is a pollution-free clean production process.