The invention belongs to the technical field of quilting machines, in particular to a quilting machine. The quilting machine comprises a machine frame, wherein the machine frame comprises a rack and an upper machine frame which is arranged at the upper end of the rack, the machine frame is provided with multi-needle machine heads which can be displaced in the longitudinal direction, a rotating shuttle mechanism is arranged below the multi-needle machine heads, the machine frame is provided with a first drive mechanism which drives the multi-needle machine heads and the rotating shuttle mechanism to conduct synchronous movement, the multi-needle machine heads are slidably connected to the upper machine frame, the rotating shuttle mechanism is slidably connected to the rack, and the machine frame is further provided with a second drive mechanism which drives cloth to conduct crossing feed. According to the quilting machine, the arraying directions of the multi-needle machine heads are vertical to the feeding direction of the cloth, the situation that during seaming, the seaming stitches of two adjacent needle heads do not interfere with each other is guaranteed, joint points do not form wired nodes, the situation that the node places are prone to off-line is avoided, the quality and attractiveness of a product are guaranteed, multiple sewing needle heads work together, and thus the producing efficiency is improved.