The invention relates to a power supply chip management system and a power supply chip management method. The power supply chip management method comprises the following steps: detecting a to-be-displayed image, and acquiring gray-scale values of various pixel points of the to-be-displayed image; in accordance with the gray-scale values of the pixel points, searching a voltage parameter lookup table, and acquiring voltages of the various pixel points, wherein corresponding relations between the gray-scale values and the voltages are saved in the voltage parameter look-up table; in accordance with the voltages of the various pixel points, calculating load voltage of a screen body, and calculating a load current value of the screen body in accordance with the load voltage of the screen body and screen body resistance of a display panel; and regulating an output duty ratio of a pulse modulating signal in accordance with the load current value of the screen body so as to regulate output voltage of a power supply chip. With the application of the power supply chip management method, efficiency of the power supply chip under different loads is greatly improved; and the power supply chip is stable in efficiency and free from influence of load current, so that the display effect of an OLED (organic light emitting diode) panel is effectively guaranteed. The invention also provides a corresponding power supply chip management system.