The invention belongs to high-voltage switch equipment and relates to a circuit breaker-disconnecting switch operation interlocking mechanism. The mechanism comprises a disconnecting switch operation shaft, wherein two clamp grooves are formed in an outer cylindrical surface of the disconnecting switch operation shaft; a linkage connecting lever is arranged outside the disconnecting switch operation shaft, and a fixed pivot shaft is arranged at the rear end of the linkage connecting lever; the middle of the linkage connecting lever and a pull rod hinged with the linkage connecting lever are connected with a breaking-closing action part of a circuit breaker, and the linkage connecting lever can be driven to swing up and down around the pivot shaft by the switch off-switch on actions of the circuit breaker; and a hanger protruding towards the disconnecting switch operation shaft is arranged at the front end of the linkage connecting lever, and when the disconnecting switch operation shaft is located at a switch off position and a switch on position of a disconnecting switch, the hanger is respectively aligned to two clamp grooves and can be clamped into the clamp grooves in a switch on state of the circuit breaker. The circuit breaker-disconnecting switch operation interlocking mechanism is simple in structure, convenient to manufacture and mount and high in locking reliability.