The invention discloses a charging control circuit for a mobile power supply. The charging control circuit includes an AC charging module U3, an electric core module, an MCU and a protection board module U4; the AC charging module U3 is connected with the MCU through a signal regulating circuit, the AC charging module U3 is connected with the electric core module through a switch tube Q1, the MCU is connected with the switch tube Q1, and the protection board module U4 is connected with the AC charging module U3 through a resistor R3; the signal regulating circuit includes an amplifier U2, a filter circuit U5 and a comparator U1, the MCU is connected with the comparator U1 through the filter circuit U5, the comparator U1 is connected with the AC charging module U3, one end of the amplifier U2 is connected with the AC charging module U3 through the resistor R3, and the other end of the amplifier U2 is connected with the comparator U1. According to the charging control circuit for the mobile power supply, a PWM is controlled to manage AC charging current, the AC charging module U3 is directly used for charging the electric core module, the magnitude of the charging current can be adjusted, management is no longer directed at output voltage of AC charging module U3, and a DC voltage reduction module is omitted.