The invention provides an assessment method of multicycle carbon dioxide huff-puff for thickened oil edge-bottom water reservoir. The assessment method has the steps that actual parameter of each factor in real reservoir is measured as gist, reservoir model is established, huff-puff mine oil production and non-huff-puff mine oil production are simulated and obtained, huff-puff oil increment is obtained; huff-puff oil increment is used as evaluating association object, amendment weight of each factor is calculated and computing method of membership is established, evaluation matrix of modeling scheme and real scheme is obtained, amendment weight of each factor is reunited, average value of synthesis score of all factor with each modeling scheme and real scheme and Cj are calculated and sorted. The assessment method can solve the problem of difficult evaluation of weight brought from incomplete in-situ data, difficult calculation of evaluation matrix, short gist of evaluation limit and unreasonable evaluation result, and has significance for directing and conducting reasonable evaluation of multicycle carbon dioxide huff-puff for thickened oil edge-bottom water reservoir.