The invention provides a waterproof door for a distribution room. The waterproof door for the distribution room comprises a door frame, a main door and an air pressure sealing strip, wherein the door frame is arranged on a wall of the distribution room; the main door is arranged on the door frame in a rotatable form; the air pressure sealing strip is arranged on the main door; and when the main door is closed, the air pressure sealing strip is inflated so as to seal a gap between the main door and the door frame. In a working process, after the main door is closed, the interior of the air pressure sealing strip is inflated by a worker, so that the volume of the air pressure sealing strip is increased and the gap between the main door and the door frame is blocked.