The invention provides a bottom-hole blocking device. The bottom-hole blocking device comprises a first oil pipe, a casing packer, a third oil pipe, a releasing packer, a fourth oil pipe, an open hole packer and a second oil pipe, wherein the casing packer is used for setting the bottom end of casing section in an oil well; the open hole packer is used for setting the upper part of an effective oil-yielding stratum of an open hole section in the oil well; the bottom end of the first oil pipe is communicated with the top end of the casing packer; the top end of the releasing packer is communicated with the bottom end of the casing packer through the third oil pipe; the bottom end of the releasing packer is communicated with the top end of the open hole packer through the fourth oil pipe; the top end of the second oil pipe is communicated with the bottom end of the open hole packer; the bottom end of the second oil pipe is positioned in the middle of the effective oil-yielding stratum. The bottom-hole blocking device has the advantages that the releasing packer is arranged between the casing packer and the open hole packer, after oil extraction, the releasing packer can be directly opened to enable the oil pipe on the upper side of the releasing packer to be separated from the releasing packer, both the releasing packer and the open hole packer can be fished out through only one fishing tool matched with the releasing packer, the fishing time is shortened, and the fishing efficiency is improved.