The invention relates to a toothbrush capable of automatically cleaning. The toothbrush comprises a tooth die, wherein the two tooth die comprises two parts, namely an upper part and a lower part which are used for accommodating upper teeth and lower teeth; the tooth die is connected to the handle on the front side of the handle so as to hold the tooth handle and enable all other related functions to take effect; the handle comprises two pipes; one pipe is used for filling liquid toothpaste, and the other pipe is used for sucking wastes after cleaning. The device is started, so that the liquid toothpaste penetrates through the corresponding pipe and is pumped towards the tooth die, so that cylindrical toothbrushes on the front inner side and the back inner side of the two parts of the tooth die and toothbrushes positioned in the middle of the tooth die are fixed; the two toothbrushes fixed on the two inner sides of the tooth die rotate around metal flexible shafts of the toothbrushes along an opposite direction of gingival; by using a motor with gears, flexible lines on which the gears are fixed can move; moreover, the toothbrushes in the middle of the tooth die mutually move, as all the toothbrushes are fixed on the corresponding gears by which the toothbrushes move one by one; the tooth die is provided with holes, so that dist is sucked into the pipe fixed on the handle when a cleaning process is ended.