The invention provides a sealed bending-winding-resistant pumping rod and a pumping rod manufacturing method, and belongs to the technical field of oil exploitation equipment. The sealed bending-winding-resistant pumping rod comprises a plurality of first elastic macromolecule protection sleeves, a second elastic macromolecule protection sleeve and a steel wire rope, and the steel wire rope comprises a plurality of strands of steel wire cables. The first elastic macromolecule protection sleeves and the second elastic macromolecule protection sleeve are made from corrosion-resistant materials with elasticity and toughness, each steel wire cable is nested in the corresponding first elastic macromolecule protection sleeve in an injection molding mode, the steel wire rope is formed by winding the steel wire cables which are nested in the first elastic macromolecule protection sleeves, and the steel wire rope is nested in the second elastic macromolecule protection sleeve in an injection molding mode. The steel wire cables are nested in the first elastic macromolecule protection sleeves in the injection molding mode, the steel wire cables nested in the first elastic macromolecule protection sleeves are wound to form the steel wire rope which is nested in the second elastic macromolecule protection sleeve in the injection molding mode, and therefore the service life of the sealed bending-winding-resistant pumping rod is prolonged, and the adaptability of the sealed bending-winding-resistant pumping rod is improved.