The invention provides a deep sea natural gas hydrate exploitation control method. By exploitation of natural gas hydrates on the basis of a solid exploitation method, the method includes: crushing natural gas hydrate reserves into particles; performing solid-liquid two-phase hydraulic lifting through ejected seawater; keeping a stable state of the natural gas hydrates through a temperature and pressure maintaining control device arranged in a vertical exploitation pipeline; lifting through a closed pipeline to the sea surface to realize separation treatment. The method has advantages that safety and quickness in delivery of the deep sea natural gas hydrates in the exploitation pipeline can be realized, and potential hazards caused by decomposition of the natural gas hydrates in the high-temperature exploitation pipeline are avoided.