The invention discloses a method for controlling an optical fiber screening device pay-off rack to be automatically loaded and unloaded on a plate. The method includes the steps that a control system achieves communication between an optical fiber screening device and an intelligent logistics system through an MES system; the control system controls the moving of the intelligent logistics system, and when the intelligent logistics system moves to a target position, the intelligent logistics system is controlled to take corresponding actions; the control system controls the moving of the optical fiber screening device, and a pay-off rack clamping mechanism of the optical fiber screening device can conduct clamping or opening operation; the controls system controls the moving of the intelligent logistics system and controls the intelligent logistics system to take corresponding actions after the optical fiber screening device sends out instructions. By means of the method, the optical fiber screening device pay-off rack can be automatically loaded and unloaded on the plate, and the problems that an existing plate loading and unloading mode is low in efficiency and certain hidden safety hazards exist in the plate loading process are solved. The invention further discloses a system for controlling the optical fiber screening device pay-off rack to be automatically loaded and unloaded on the plate.