The invention discloses a coal and rock mass multi-parameter monitoring test device based on true triaxial loading. The coal and rock mass multi-parameter monitoring test device based on the true triaxial loading comprises a pressure cavity, four horizontal stress loading oil cylinders and a vertical stress loading oil cylinder; four horizontal stress loading holes are formed in the side wall of the pressure cavity; a vertical stress loading hole is formed in a bottom plate; a sample assembling and disassembling passing hole and a detachable type sealing cover plate are arranged in/on a top plate; a stress loading pressure rod is installed in each stress loading hole and is matched with each stress loading hole in a sealing and sliding matching manner; pressure heads are installed at the inner end of each pressure rod and on the lower surface of the sealing cover plate respectively; an acoustic emission probe is installed on the side surface of each pressure head; a micro-electro sensitive nickel-cobalt pole piece is installed on the inner surface of the pressure cavity; a stress sensor is installed between each stress loading pressure rod and a corresponding oil cylinder piston rod; a rigid connection cylinder is installed between each oil cylinder body and the outer wall of the pressure cavity; a grating sensor is installed between each stress loading pressure rod and the corresponding rigid connection cylinder; a signal transmission socket is installed on the side wall of the pressure cavity and is provided with an electric signal transmission interface and an acoustic emission transmission interface separately; and the pressure heads are arranged into a plurality of groups according to different sizes.